BDBM6573 (5-Methoxy-1H-2-indolyl)(1H-2-indolyl)methanone::2-(1H-indol-2-ylcarbonyl)-5-methoxy-1H-indole::Bis(1H-2-indolyl)methanone 11::CHEMBL7296

SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1

InChI Key InChIKey=QTIQVLAVCXXZPS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 6573   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
University Of Regensburg

LigandPNGBDBM6573((5-Methoxy-1H-2-indolyl)(1H-2-indolyl)methanone | ...)
Affinity DataIC50:  300nMpH: 7.4 T: 2°CAssay Description:The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM6573((5-Methoxy-1H-2-indolyl)(1H-2-indolyl)methanone | ...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM6573((5-Methoxy-1H-2-indolyl)(1H-2-indolyl)methanone | ...)
Affinity DataIC50:  300nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed