BDBM65841 2-(trifluoromethyl)-10H-phenothiazine::SR-01000441858-2::cid_7082

SMILES: FC(F)(F)c1ccc2Sc3ccccc3Nc2c1

InChI Key: InChIKey=RKGYJVASTMCSHZ-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 65841   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NADPH oxidase 1 (Homo sapiens (Human))	BDBM65841 (2-(trifluoromethyl)-10H-phenothiazine | SR-0100044...) Show SMILES FC(F)(F)c1ccc2Sc3ccccc3Nc2c1 Show InChI InChI=1S/C13H8F3NS/c14-13(15,16)8-5-6-12-10(7-8)17-9-3-1-2-4-11(9)18-12/h1-7,17H	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2RF5SGM
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM65841 (2-(trifluoromethyl)-10H-phenothiazine | SR-0100044...) Show SMILES FC(F)(F)c1ccc2Sc3ccccc3Nc2c1 Show InChI InChI=1S/C13H8F3NS/c14-13(15,16)8-5-6-12-10(7-8)17-9-3-1-2-4-11(9)18-12/h1-7,17H	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	2.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2GX490H
					More data for this Ligand-Target Pair
Cytochrome b-245 heavy chain (Homo sapiens (Human))	BDBM65841 (2-(trifluoromethyl)-10H-phenothiazine | SR-0100044...) Show SMILES FC(F)(F)c1ccc2Sc3ccccc3Nc2c1 Show InChI InChI=1S/C13H8F3NS/c14-13(15,16)8-5-6-12-10(7-8)17-9-3-1-2-4-11(9)18-12/h1-7,17H	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q25719HD
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM65841 (2-(trifluoromethyl)-10H-phenothiazine | SR-0100044...) Show SMILES FC(F)(F)c1ccc2Sc3ccccc3Nc2c1 Show InChI InChI=1S/C13H8F3NS/c14-13(15,16)8-5-6-12-10(7-8)17-9-3-1-2-4-11(9)18-12/h1-7,17H	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	Purchase PC cid PC sid UniChem Similars	Article PCBioAssay	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...				PubChem Bioassay (2010) Article DOI: 10.1016/j.bioorg.2014.08.007 BindingDB Entry DOI: 10.7270/Q2XP73CQ
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM65841 (2-(trifluoromethyl)-10H-phenothiazine | SR-0100044...) Show SMILES FC(F)(F)c1ccc2Sc3ccccc3Nc2c1 Show InChI InChI=1S/C13H8F3NS/c14-13(15,16)8-5-6-12-10(7-8)17-9-3-1-2-4-11(9)18-12/h1-7,17H	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2JD4V7Q
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM65841 (2-(trifluoromethyl)-10H-phenothiazine | SR-0100044...) Show SMILES FC(F)(F)c1ccc2Sc3ccccc3Nc2c1 Show InChI InChI=1S/C13H8F3NS/c14-13(15,16)8-5-6-12-10(7-8)17-9-3-1-2-4-11(9)18-12/h1-7,17H	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2SX6BN0
					More data for this Ligand-Target Pair