BDBM6623 3-{5-[(tert-butylamino)methyl]-1H-pyrazol-3-yl}-1-{5-oxo-1H,2H,3H,5H,9bH-benzo[a]pyrrolizin-9-yl}urea::5-alkylaminomethyl pyrazole-3-yl urea deriv. 9d::N-{5-[(tert-Butylamino)methyl]-1H-pyrazol-3-yl}-N -(5-oxo-2,3,5,9b-tetrahydro-1H-pyrrolo[2,1-a]isoindol-9-yl)-urea

SMILES CC(C)(C)NCc1cc(NC(=O)Nc2cccc3C(=O)N4CCCC4c23)[nH]n1

InChI Key InChIKey=GTZWWDDACCTQQM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6623   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Homo sapiens (Human))
Banyu Tsukuba Research Institute

LigandPNGBDBM6623(3-{5-[(tert-butylamino)methyl]-1H-pyrazol-3-yl}-1-...)
Affinity DataIC50:  56nMAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

LigandPNGBDBM6623(3-{5-[(tert-butylamino)methyl]-1H-pyrazol-3-yl}-1-...)
Affinity DataIC50:  9.80E+3nMAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed