BDBM6665 6-[(2,6-dichlorophenyl)carbonyl]-N-[3-(methylsulfanyl)phenyl]imidazo[1,2-a]pyridin-2-amine::aminoimidazo[1,2-a]pyridine deriv. 2d

SMILES CSc1cccc(Nc2cn3cc(ccc3n2)C(=O)c2c(Cl)cccc2Cl)c1

InChI Key InChIKey=VIIKIFKPRYMNGG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 6665   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM6665(6-[(2,6-dichlorophenyl)carbonyl]-N-[3-(methylsulfa...)
Affinity DataIC50:  1.77E+4nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM6665(6-[(2,6-dichlorophenyl)carbonyl]-N-[3-(methylsulfa...)
Affinity DataIC50:  1.19E+4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM6665(6-[(2,6-dichlorophenyl)carbonyl]-N-[3-(methylsulfa...)
Affinity DataIC50:  4.80E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed