BDBM6716 1,4,14,25-tetraazaheptacyclo[16.9.1.0^{2,17}.0^{3,11}.0^{5,10}.0^{12,16}.0^{22,28}]octacosa-2(17),3(11),5(10),6,8,12(16),18(28),19,21-nonaene-13,15-dione hydrochloride::aza-1,7-annulated indole deriv. 21

SMILES O=C1NC(=O)c2c1c1c3ccccc3[nH]c1c1n3CCNCCc4cccc(c34)c21

InChI Key InChIKey=KDNVBMSJXYVRKD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 6716   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM6716(1,4,14,25-tetraazaheptacyclo[16.9.1.0^{2,17}.0^{3,...)
Affinity DataIC50:  160nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed