BDBM678 3-{4-[(2S,3R)-2-{[(tert-butoxy)carbonyl]amino}-4-{[(2R,3S)-3-{[(tert-butoxy)carbonyl]amino}-2-hydroxy-4-phenylbutyl]amino}-3-hydroxybutyl]phenoxy}propanoic acid::BMS-186318 analog 15::[1S-[1R*,2S*(2S*,3R*)]]-[4-[4-(Carboxymethoxy)phenyl]-3-[[3-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxy-1-(phenylmethyl)propyl)carbamic Acid, 1,1-Dimethylethyl Ester
SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)[C@H](O)CNC[C@@H](O)[C@H](Cc1ccc(OCCC(O)=O)cc1)NC(=O)OC(C)(C)C
InChI Key InChIKey=PJSBMULNVPRXJP-YVHASNINSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 678
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Bristol-Myers Squibb
Bristol-Myers Squibb
Affinity DataIC50: 150nMpH: 5.5 T: 2°CAssay Description:IC50 values are determined by inhibition of the cleavage of the peptidic substrate [V-S-Q-N-(beta-naphthylalanine)-P-I-V]. The IC50 value represents ...More data for this Ligand-Target Pair