BDBM68256 Microlactone, 15c

SMILES C[C@@H]1C\C=C\CCCCC(=O)Cc2c(Cl)c(O)cc(O)c2C(=O)O1

InChI Key InChIKey=MAIXLHSZNVDUIV-JOAKQRRISA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 68256   

TargetATP-dependent molecular chaperone HSP82(Saccharomyces cerevisiae)
University Of Nottingham

LigandPNGBDBM68256(Microlactone, 15c)
Affinity DataIC50: <1.00E+3nMAssay Description:A colorimetric assay for the release of inorganic phosphate upon hydrolysis of ATP was used to determine the potency of Hsp 90 inhibitor against enzy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent molecular chaperone HSP82(Saccharomyces cerevisiae)
University Of Nottingham

LigandPNGBDBM68256(Microlactone, 15c)
Affinity DataIC50:  100nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent molecular chaperone HSP82(Saccharomyces cerevisiae)
University Of Nottingham

LigandPNGBDBM68256(Microlactone, 15c)
Affinity DataIC50:  1.00E+3nMAssay Description:A colorimetric assay for the release of inorganic phosphate upon hydrolysis of ATP was used to determine the potency of Hsp 90 inhibitor against enzy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed