BDBM75364 4-(phenylmethyl)-N-(4-sulfamoylphenyl)-1-piperazinecarboxamide::4-(phenylmethyl)-N-(4-sulfamoylphenyl)piperazine-1-carboxamide::4-benzyl-N-(4-sulfamoylphenyl)piperazine-1-carboxamide::MLS-0435629.0001::cid_27869236

SMILES NS(=O)(=O)c1ccc(NC(=O)N2CCN(Cc3ccccc3)CC2)cc1

InChI Key InChIKey=VJPQXXSBUBPQDB-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 75364   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM75364(4-(phenylmethyl)-N-(4-sulfamoylphenyl)-1-piperazin...)
Affinity DataKi:  6.5nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM75364(4-(phenylmethyl)-N-(4-sulfamoylphenyl)-1-piperazin...)
Affinity DataKi:  50nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM75364(4-(phenylmethyl)-N-(4-sulfamoylphenyl)-1-piperazin...)
Affinity DataKi:  149nMAssay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM75364(4-(phenylmethyl)-N-(4-sulfamoylphenyl)-1-piperazin...)
Affinity DataKi:  462nMAssay Description:Inhibition of human carbonic anhydrase 9 preincubated for 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM75364(4-(phenylmethyl)-N-(4-sulfamoylphenyl)-1-piperazin...)
Affinity DataIC50: >1.00E+5nMAssay Description:Data Source: Burnham Center for Chemical Genomics (BCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) Networ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM75364(4-(phenylmethyl)-N-(4-sulfamoylphenyl)-1-piperazin...)
Affinity DataIC50:  1.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay