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BDBM75814 MLS000539595::N-[(E)-1-[[(4-methylbenzylidene)amino]carbamoyl]-2-[(4-methylpyrimidin-2-yl)amino]vinyl]benzamide::N-[(E)-3-[2-[(4-methylphenyl)methylidene]hydrazinyl]-1-[(4-methyl-2-pyrimidinyl)amino]-3-oxoprop-1-en-2-yl]benzamide::N-[(E)-3-[2-[(4-methylphenyl)methylidene]hydrazinyl]-1-[(4-methylpyrimidin-2-yl)amino]-3-oxidanylidene-prop-1-en-2-yl]benzamide::N-[(E)-3-[2-[(4-methylphenyl)methylidene]hydrazinyl]-1-[(4-methylpyrimidin-2-yl)amino]-3-oxoprop-1-en-2-yl]benzamide::N-{1-({2-[(4-methylphenyl)methylene]hydrazino}carbonyl)-2-[(4-methyl-2-pyrimidinyl)amino]vinyl}benzenecarboxamide::SMR000125253::cid_2768717

SMILES: Cc1ccc(C=NNC(=O)C(NC(=O)c2ccccc2)C=Nc2nccc(C)n2)cc1

InChI Key: InChIKey=JNOMJBROIFBILT-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 75814   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
insulin-degrading enzyme isoform 1 precursor


(Homo sapiens)
BDBM75814
PNG
(MLS000539595 | N-[(E)-1-[[(4-methylbenzylidene)ami...)
Show SMILES Cc1ccc(C=NNC(=O)C(NC(=O)c2ccccc2)C=Nc2nccc(C)n2)cc1
Show InChI InChI=1S/C23H22N6O2/c1-16-8-10-18(11-9-16)14-26-29-22(31)20(15-25-23-24-13-12-17(2)27-23)28-21(30)19-6-4-3-5-7-19/h3-15,20H,1-2H3,(H,28,30)(H,29,31)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a 5.43E+3n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2416VHJ
More data for this
Ligand-Target Pair