BDBM7766 (12Z)-12-{[(4-methanesulfonylphenyl)amino]methylidene}-3-thia-5,10-diazatricyclo[7.3.0.0^{2,6}]dodeca-1,4,6,8-tetraen-11-one::8-{[4-(Methylsulfonyl)anilino]methylene}-6,8-dihydro-7H-[1,3]thiazolo[5,4-e]indol-7-one::Oxindole-Based Inhibitor 102

SMILES CS(=O)(=O)c1ccc(cc1)N=CC1C(=O)Nc2ccc3ncsc3c12

InChI Key InChIKey=PQNZDZNQKSSWPV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 7766   

TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM7766((12Z)-12-{[(4-methanesulfonylphenyl)amino]methylid...)
Affinity DataIC50:  5.70nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM7766((12Z)-12-{[(4-methanesulfonylphenyl)amino]methylid...)
Affinity DataIC50:  39nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed