BDBM7779 4-butyl-2-ethyl-1,2,4-thiadiazolidine-3,5-dione::4-n-Butyl-2-ethyl-1,2,4-thiadiazolidine-3,5-dione::Thiadiazolidinone (TDZD) deriv. 6

SMILES CCCCn1c(=O)sn(CC)c1=O

InChI Key InChIKey=WTFFYZGCISALRI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 7779   

TargetGlycogen synthase kinase-3 beta [7-25](Oryctolagus cuniculus (rabbit))
Instituto De Quimica Medica (Csic)

LigandPNGBDBM7779(4-butyl-2-ethyl-1,2,4-thiadiazolidine-3,5-dione | ...)
Affinity DataIC50:  7.00E+4nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7779(4-butyl-2-ethyl-1,2,4-thiadiazolidine-3,5-dione | ...)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRegulator of G-protein signaling 8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7779(4-butyl-2-ethyl-1,2,4-thiadiazolidine-3,5-dione | ...)
Affinity DataIC50:  8.35E+4nMAssay Description:Inhibition of RGS8 interaction with Galpha0 protein by flow cytometry protein interaction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRegulator of G-protein signaling 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7779(4-butyl-2-ethyl-1,2,4-thiadiazolidine-3,5-dione | ...)
Affinity DataIC50:  14nMAssay Description:Inhibition of RGS4 interaction with Galpha0 protein by flow cytometry protein interaction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed