BDBM7874 2-chloro-1-(4-chlorophenyl)ethan-1-one::Halomethyl Phenyl Ketone deriv. 22

SMILES ClCC(=O)c1ccc(Cl)cc1

InChI Key InChIKey=FWDFNLVLIXAOMX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 7874   

TargetGlycogen synthase kinase-3 beta [7-25](Oryctolagus cuniculus (rabbit))
Instituto De Quimica Medica (Csic)

LigandPNGBDBM7874(2-chloro-1-(4-chlorophenyl)ethan-1-one | Halomethy...)
Affinity DataIC50:  2.50E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Instituto De Qui£?Mica Medica-Csic

Curated by ChEMBL
LigandPNGBDBM7874(2-chloro-1-(4-chlorophenyl)ethan-1-one | Halomethy...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of GSK3beta using GS1 as substrate and [gamma-32P]ATP after 20 mins by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Instituto De Qui£?Mica Medica-Csic

Curated by ChEMBL
LigandPNGBDBM7874(2-chloro-1-(4-chlorophenyl)ethan-1-one | Halomethy...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of glycogen synthase kinase-3 beta (unknown origin) using GS-1 as substrate after 20 mins by scintillation counting analysis in presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed