BDBM7876 2-bromo-1-(4-bromophenyl)ethan-1-one::Halomethyl Phenyl Ketone deriv. 24::p-bromophenacyl bromide

SMILES BrCC(=O)c1ccc(Br)cc1

InChI Key InChIKey=FKJSFKCZZIXQIP-UHFFFAOYSA-N

Data  4 IC50

PDB links: 4 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 7876   

TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Instituto De Quimica Medica (Csic)

LigandPNGBDBM7876(2-bromo-1-(4-bromophenyl)ethan-1-one | Halomethyl ...)
Affinity DataIC50:  500nMT: 37°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Human)
Instituto De Qui£?Mica Medica-Csic

Curated by ChEMBL
LigandPNGBDBM7876(2-bromo-1-(4-bromophenyl)ethan-1-one | Halomethyl ...)
Affinity DataIC50:  500nMAssay Description:Inhibition of GSK3beta using GS1 as substrate and [gamma-32P]ATP after 20 mins by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Human)
Instituto De Qui£?Mica Medica-Csic

Curated by ChEMBL
LigandPNGBDBM7876(2-bromo-1-(4-bromophenyl)ethan-1-one | Halomethyl ...)
Affinity DataIC50:  500nMAssay Description:Inhibition of glycogen synthase kinase-3 beta (unknown origin) using GS-1 as substrate after 20 mins by scintillation counting analysis in presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Human)
University of California San Diego

LigandPNGBDBM7876(2-bromo-1-(4-bromophenyl)ethan-1-one | Halomethyl ...)
Affinity DataIC50:  5.50E+5nMpH: 9.0 T: 40°CAssay Description:Inhibition assay using phospholipase A2.More data for this Ligand-Target Pair
In DepthDetails PubMed