BDBM8117 Hydroxyethylene Sulfone 17b::N-[(2S,3R,5S)-1-(3-bromophenyl)-5-[(4-fluorobenzene)sulfonyl]-3-hydroxy-7-methyloctan-2-yl]-2-(2,6-dimethylphenoxy)acetamide::N-{(1S,2R,4S)-1-(3-bromobenzyl)-4-[(4-fluorophenyl)sulfonyl]-2-hydroxy-6-methylheptyl}-2-(2,6-dimethylphenoxy)acetamide

SMILES CC(C)C[C@@H](C[C@@H](O)[C@H](Cc1cccc(Br)c1)NC(=O)COc1c(C)cccc1C)S(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=RVHWPGAHEOLZNT-YTCPBCGMSA-N

Data  1 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 8117   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Philipps-Universitat Marburg

LigandPNGBDBM8117(Hydroxyethylene Sulfone 17b | N-[(2S,3R,5S)-1-(3-b...)
Affinity DataKi:  45nM ΔG°:  -10.0kcal/mole IC50:  85nMpH: 5.5 T: 2°CAssay Description:The inhibition assays were performed by mixing enzyme and fluorogenic substrate in the presence of inhibitor compounds. The hydrolysis of the substra...More data for this Ligand-Target Pair