BDBM8117 Hydroxyethylene Sulfone 17b::N-[(2S,3R,5S)-1-(3-bromophenyl)-5-[(4-fluorobenzene)sulfonyl]-3-hydroxy-7-methyloctan-2-yl]-2-(2,6-dimethylphenoxy)acetamide::N-{(1S,2R,4S)-1-(3-bromobenzyl)-4-[(4-fluorophenyl)sulfonyl]-2-hydroxy-6-methylheptyl}-2-(2,6-dimethylphenoxy)acetamide
SMILES CC(C)C[C@@H](C[C@@H](O)[C@H](Cc1cccc(Br)c1)NC(=O)COc1c(C)cccc1C)S(=O)(=O)c1ccc(F)cc1
InChI Key InChIKey=RVHWPGAHEOLZNT-YTCPBCGMSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 8117
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Philipps-Universitat Marburg
Philipps-Universitat Marburg
Affinity DataKi: 45nM ΔG°: -10.0kcal/mole IC50: 85nMpH: 5.5 T: 2°CAssay Description:The inhibition assays were performed by mixing enzyme and fluorogenic substrate in the presence of inhibitor compounds. The hydrolysis of the substra...More data for this Ligand-Target Pair