BDBM81736 PPY-C

SMILES COc1ccccc1-c1c[nH]c2ncc(cc12)-c1cccc(NC(C)=O)c1

InChI Key InChIKey=BLZJCDJMIBXBBX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 81736   

TargetTyrosine-protein kinase ABL1 [T315I](Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM81736(PPY-C)
Affinity DataIC50:  41nMpH: 7.4 T: 2°CAssay Description:Inhibition of wild-type Abl and Abl T315I kinase activity was measured in a homogeneous time-resolved fluorescence resonance energy transfer (TR-FRET...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM81736(PPY-C)
Affinity DataIC50:  110nMpH: 7.4 T: 2°CAssay Description:Inhibition of wild-type Abl and Abl T315I kinase activity was measured in a homogeneous time-resolved fluorescence resonance energy transfer (TR-FRET...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed