BDBM81986 3-Methyl-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrochloride::CAS_173870::CHEMBL545000::NSC_173870::SKF 75670

SMILES CN1CCc2cc(O)c(O)cc2C(C1)c1ccccc1

InChI Key InChIKey=LIHCKGZEDBNUJG-UHFFFAOYSA-N

Data  4 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 81986   

TargetD(1A) dopamine receptor(Mus musculus (Mouse))
Novo Industri

Curated by PDSP Ki Database
LigandPNGBDBM81986(3-Methyl-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]az...)
Affinity DataKi:  1.90nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM81986(3-Methyl-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]az...)
Affinity DataKi:  8.80nMAssay Description:The compound was evaluated for the dissociation constant for inhibiting the binding of [3H]-SCH- 23390 at dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Novo Industri

Curated by PDSP Ki Database
LigandPNGBDBM81986(3-Methyl-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]az...)
Affinity DataKi:  840nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM81986(3-Methyl-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]az...)
Affinity DataKi:  1.90E+3nMAssay Description:The compound was evaluated for the binding affinity towards dopamine receptor D2 at high affinity state.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM81986(3-Methyl-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]az...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human dopamine D1 receptor expressed in CHOK1 cells assessed as assessed as increase in beta-arrestin-2 recruitment after 60 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM81986(3-Methyl-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]az...)
Affinity DataEC50:  0.450nMAssay Description:Agonist activity at human dopamine D1 receptor expressed in CHOK1 cells assessed as reversal of Ro 20-1724 mediated decrease in cAMP accumulation aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed