BDBM82068 CHEMBL9732::Nicotine-D salicylate::Nicotine-L salicylate

SMILES CN1CCC[C@@H]1c1cccnc1

InChI Key InChIKey=SNICXCGAKADSCV-SNVBAGLBSA-N

Data  5 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 82068   

TargetNicotinic acetylcholine receptor(RAT)
R. J. Reynolds Tobacco

Curated by PDSP Ki Database
LigandPNGBDBM82068(CHEMBL9732 | Nicotine-D salicylate | Nicotine-L sa...)
In DepthDetails PubMed
TargetNicotinic acetylcholine receptor(RAT)
R. J. Reynolds Tobacco

Curated by PDSP Ki Database
LigandPNGBDBM82068(CHEMBL9732 | Nicotine-D salicylate | Nicotine-L sa...)
Affinity DataKi:  35nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM82068(CHEMBL9732 | Nicotine-D salicylate | Nicotine-L sa...)
Affinity DataKi:  38nMAssay Description:Inhibition of [3H]-epibatidine binding to Nicotinic acetylcholine receptor alpha4-beta2 from rat membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM82068(CHEMBL9732 | Nicotine-D salicylate | Nicotine-L sa...)
Affinity DataKi:  87nMAssay Description:In vitro inhibition of [3H]-Cytisine binding in rat brain tissue at Nicotinic acetylcholine receptor alpha4-beta2 at 100 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinic acetylcholine receptor(RAT)
R. J. Reynolds Tobacco

Curated by PDSP Ki Database
LigandPNGBDBM82068(CHEMBL9732 | Nicotine-D salicylate | Nicotine-L sa...)
Affinity DataKi:  145nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 2A5(Mus musculus)
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM82068(CHEMBL9732 | Nicotine-D salicylate | Nicotine-L sa...)
Affinity DataIC50:  1.60E+5nMAssay Description:Inhibitory concentration against mouse cytochrome P450 2A5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinic acetylcholine receptor alpha 5 subunit(Musca domestica)
Gifu University

Curated by ChEMBL
LigandPNGBDBM82068(CHEMBL9732 | Nicotine-D salicylate | Nicotine-L sa...)
Affinity DataIC50:  4.22E+5nMAssay Description:Displacement of [3HIMI from nicotinic acetylcholine receptor in Musca domestica (house fly) head membranes incubated for 60 min by liquid scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM82068(CHEMBL9732 | Nicotine-D salicylate | Nicotine-L sa...)
Affinity DataIC50:  5.80E+5nMAssay Description:Inhibitory concentration against human cytochrome P450 2A6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed