BDBM82157 7-substituted pyrazoloquinolone, 16

SMILES CN(C)c1ccc2nc3cc([nH]n3c(=O)c2c1)C(O)=O

InChI Key InChIKey=LGDUXRISMGXHSP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 82157   

TargetPhosphopantetheine adenylyltransferase(Escherichia coli)
Pfizer

LigandPNGBDBM82157(7-substituted pyrazoloquinolone, 16)
Affinity DataIC50:  4.90E+4nMAssay Description:PPAT screening assay (forward-direction assay) were performed in clear 384 well plates containing in each well either 1-uL DMSO, 1 uL of variable con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphopantetheine adenylyltransferase(Escherichia coli)
Pfizer

LigandPNGBDBM82157(7-substituted pyrazoloquinolone, 16)
Affinity DataIC50:  7.10E+3nMAssay Description:The reverse assay was performed in polyproplene 96-well plates containing in each well either 1 uL DMSO, 1 UL of variable concentrations of test comp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphopantetheine adenylyltransferase(Enterococcus faecalis (Streptococcus faecalis))
Pfizer

LigandPNGBDBM82157(7-substituted pyrazoloquinolone, 16)
Affinity DataIC50:  1.57E+5nMAssay Description:PPAT screening assay (forward-direction assay) were performed in clear 384 well plates containing in each well either 1-uL DMSO, 1 uL of variable con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed