BDBM8224 3-[(3-chlorophenyl)amino]-4-phenyl-2,5-dihydro-1H-pyrrole-2,5-dione::4-arylmaleimide deriv. 6g

SMILES Clc1cccc(NC2=C(C(=O)NC2=O)c2ccccc2)c1

InChI Key InChIKey=WCAYCTGIGMRVKS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8224   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University Of Jordan

Curated by ChEMBL
LigandPNGBDBM8224(3-[(3-chlorophenyl)amino]-4-phenyl-2,5-dihydro-1H-...)
Affinity DataIC50:  301nMAssay Description:Inhibition of recombinant GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM8224(3-[(3-chlorophenyl)amino]-4-phenyl-2,5-dihydro-1H-...)
Affinity DataIC50:  301nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed