BDBM82251 (R)-4-Carboxyphenylglycine::(S)-4CPG::CAS_134052-68-9

SMILES N[C@@H](C(O)=O)c1ccc(cc1)C(O)=O

InChI Key InChIKey=VTMJKPGFERYGJF-SSDOTTSWSA-N

Data  10 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 82251   

TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM82251((R)-4-Carboxyphenylglycine | (S)-4CPG | CAS_134052...)
Affinity DataKi:  3.70E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM82251((R)-4-Carboxyphenylglycine | (S)-4CPG | CAS_134052...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM82251((R)-4-Carboxyphenylglycine | (S)-4CPG | CAS_134052...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Novo Nordisk

Curated by PDSP Ki Database
LigandPNGBDBM82251((R)-4-Carboxyphenylglycine | (S)-4CPG | CAS_134052...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Novo Nordisk

Curated by PDSP Ki Database
LigandPNGBDBM82251((R)-4-Carboxyphenylglycine | (S)-4CPG | CAS_134052...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Novo Nordisk

Curated by PDSP Ki Database
LigandPNGBDBM82251((R)-4-Carboxyphenylglycine | (S)-4CPG | CAS_134052...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Novo Nordisk

Curated by PDSP Ki Database
LigandPNGBDBM82251((R)-4-Carboxyphenylglycine | (S)-4CPG | CAS_134052...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 3(RAT)
Novo Nordisk

Curated by PDSP Ki Database
LigandPNGBDBM82251((R)-4-Carboxyphenylglycine | (S)-4CPG | CAS_134052...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Novo Nordisk

Curated by PDSP Ki Database
LigandPNGBDBM82251((R)-4-Carboxyphenylglycine | (S)-4CPG | CAS_134052...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM82251((R)-4-Carboxyphenylglycine | (S)-4CPG | CAS_134052...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystine/glutamate transporter(Homo sapiens (Human))
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM82251((R)-4-Carboxyphenylglycine | (S)-4CPG | CAS_134052...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of xc-cystine-glutamate antiporter-mediated cystine uptake in human U87 cells using L-[14C]cystine as substrate after 15 mins by liquid sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed