BDBM82351 1-{[4-(substitutedphenyl/phenylethyl)piperazin1-yl]methyl}-3-methyl-1 H-indole, 3b
SMILES Cc1cn(CN2CCN(CCc3ccccc3)CC2)c2ccccc12
InChI Key InChIKey=AEYSRYMQRKDECJ-UHFFFAOYSA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 82351
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain membranes after 180 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Affinity DataKi: 14.2nM ΔG°: -11.1kcal/molepH: 7.4 T: 2°CAssay Description:The test was performed with the radioligand [3H]-(+)-pentazocine (42.5 Ci/mmol) from Perkin Elmer.More data for this Ligand-Target Pair
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Affinity DataKi: 56nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma-2 receptor in rat liver membranes after 180 mins by scintillation counting methodMore data for this Ligand-Target Pair