BDBM82351 1-{[4-(substitutedphenyl/phenylethyl)piperazin1-yl]methyl}-3-methyl-1 H-indole, 3b

SMILES Cc1cn(CN2CCN(CCc3ccccc3)CC2)c2ccccc12

InChI Key InChIKey=AEYSRYMQRKDECJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 82351   

TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Mazandaran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM82351(1-{[4-(substitutedphenyl/phenylethyl)piperazin1-yl...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain membranes after 180 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Mazandaran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM82351(1-{[4-(substitutedphenyl/phenylethyl)piperazin1-yl...)
Affinity DataKi:  14.2nM ΔG°:  -11.1kcal/molepH: 7.4 T: 2°CAssay Description:The test was performed with the radioligand [3H]-(+)-pentazocine (42.5 Ci/mmol) from Perkin Elmer.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Mazandaran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM82351(1-{[4-(substitutedphenyl/phenylethyl)piperazin1-yl...)
Affinity DataKi:  56nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma-2 receptor in rat liver membranes after 180 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed