BDBM8297 3-[(3-chloro-4-hydroxyphenyl)amino]-4-(2-nitrophenyl)-2,5-dihydro-1H-pyrrole-2,5-dione::SB-415286

SMILES Oc1ccc(NC2=C(C(=O)NC2=O)c2ccccc2N(=O)=O)cc1Cl

InChI Key InChIKey=PQCXVIPXISBFPN-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 8297   

TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM8297(3-[(3-chloro-4-hydroxyphenyl)amino]-4-(2-nitrophen...)
Affinity DataKi:  30.8nM ΔG°:  -10.1kcal/mole IC50:  77.5nMpH: 7.0 T: 2°CAssay Description:In vitro kinase inhibition assay using purified GSK-3 alpha from insect cells, was incubated at room temperature with substrate, and test compounds i...More data for this Ligand-Target Pair
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