BDBM8300 5-phenyl-1H-pyrazolo[3,4-b]pyridin-3-amine::pyrazolopyridine deriv. 3

SMILES Nc1n[nH]c2ncc(cc12)-c1ccccc1

InChI Key InChIKey=YJWFRUYKFYDTSQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8300   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University Of Jordan

Curated by ChEMBL
LigandPNGBDBM8300(5-phenyl-1H-pyrazolo[3,4-b]pyridin-3-amine | pyraz...)
Affinity DataIC50:  430nMAssay Description:Inhibition of recombinant GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM8300(5-phenyl-1H-pyrazolo[3,4-b]pyridin-3-amine | pyraz...)
Affinity DataIC50:  430nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed