BDBM8302 5-phenyl-1H-pyrazolo[3,4-c]pyridin-3-amine::pyrazolopyridine deriv. 5

SMILES Nc1n[nH]c2cnc(cc12)-c1ccccc1

InChI Key InChIKey=LZRFNYHUQSRPCO-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 8302   

TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM8302(5-phenyl-1H-pyrazolo[3,4-c]pyridin-3-amine | pyraz...)
Affinity DataIC50:  1.26E+3nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVenus kinase receptor 2(Schistosoma mansoni)
Imperial College London

Curated by ChEMBL
LigandPNGBDBM8302(5-phenyl-1H-pyrazolo[3,4-c]pyridin-3-amine | pyraz...)
Affinity DataKd:  4.70E+4nMAssay Description:Binding affinity to Schistosoma mansoni N-terminal His6-tagged full-length VKR2 kinase domain expressed in baculovirus infected Sf9 insect cells in p...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University Of Jordan

Curated by ChEMBL
LigandPNGBDBM8302(5-phenyl-1H-pyrazolo[3,4-c]pyridin-3-amine | pyraz...)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of recombinant GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed