BDBM8310 N-{5-phenyl-1H-pyrazolo[3,4-b]pyridin-3-yl}cyclopentanecarboxamide::pyrazolopyridine deriv. 13

SMILES O=C(Nc1n[nH]c2ncc(cc12)-c1ccccc1)C1CCCC1

InChI Key InChIKey=NJFATVGYCPEPCY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 8310   

TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM8310(N-{5-phenyl-1H-pyrazolo[3,4-b]pyridin-3-yl}cyclope...)
Affinity DataIC50:  5nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM8310(N-{5-phenyl-1H-pyrazolo[3,4-b]pyridin-3-yl}cyclope...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human GSK3alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University Of Jordan

Curated by ChEMBL
LigandPNGBDBM8310(N-{5-phenyl-1H-pyrazolo[3,4-b]pyridin-3-yl}cyclope...)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed