BDBM842 Benzocycloalkyl Amines deriv. 12::CHEMBL419923::tert-butyl N-[(2S,3S,5R)-5-benzyl-5-{[(1S,2S,3R)-2,3-dihydroxy-2,3-dihydro-1H-inden-1-yl]carbamoyl}-3-hydroxy-1-phenylpentan-2-yl]carbamate
SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)[C@@H](O)C[C@@H](Cc1ccccc1)C(=O)N[C@@H]1[C@H](O)[C@H](O)c2ccccc12
InChI Key InChIKey=HKAQGSPFDKETKG-HPZRALQFSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 842
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp And Dohme Research Laboratories
Merck Sharp And Dohme Research Laboratories
Affinity DataIC50: 0.100nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Universidad De Alcal£
Curated by ChEMBL
Universidad De Alcal£
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibitory activity against HIV-1 protease.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Universidad De Alcal£
Curated by ChEMBL
Universidad De Alcal£
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:In vitro inhibition of HIV-1 proteaseChecked by AuthorMore data for this Ligand-Target Pair