BDBM84555 Indirubin derivative, 30a::Indirubin derivative, 30b

SMILES CN(C)CCN(C)S(=O)(=O)c1ccc2NC(=O)C(C3=Nc4ccccc4C3(O)CC=C)c2c1

InChI Key InChIKey=SJDBWFBIDFWMRX-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 84555   

TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Schering

LigandPNGBDBM84555(Indirubin derivative, 30a | Indirubin derivative, ...)
Affinity DataIC50:  40nMpH: 8.0 T: 2°CAssay Description:Inhibition assay using CDK and selective kinases such as gsk3, EGFR, c-Kit, InsR and KDR.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Schering

LigandPNGBDBM84555(Indirubin derivative, 30a | Indirubin derivative, ...)
Affinity DataIC50:  600nMpH: 8.0 T: 2°CAssay Description:Inhibition assay using CDK and selective kinases such as gsk3, EGFR, c-Kit, InsR and KDR.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Schering

LigandPNGBDBM84555(Indirubin derivative, 30a | Indirubin derivative, ...)
Affinity DataIC50: >1.00E+4nMpH: 8.0 T: 2°CAssay Description:Inhibition assay using CDK and selective kinases such as gsk3, EGFR, c-Kit, InsR and KDR.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Schering

LigandPNGBDBM84555(Indirubin derivative, 30a | Indirubin derivative, ...)
Affinity DataIC50: >1.00E+4nMpH: 8.0 T: 2°CAssay Description:Inhibition assay using CDK and selective kinases such as gsk3, EGFR, c-Kit, InsR and KDR.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Schering

LigandPNGBDBM84555(Indirubin derivative, 30a | Indirubin derivative, ...)
Affinity DataIC50: >1.00E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition assay using CDK and selective kinases such as gsk3, EGFR, c-Kit, InsR and KDR.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Schering

LigandPNGBDBM84555(Indirubin derivative, 30a | Indirubin derivative, ...)
Affinity DataIC50: >1.00E+4nMpH: 7.0 T: 2°CAssay Description:Inhibition assay using CDK and selective kinases such as gsk3, EGFR, c-Kit, InsR and KDR.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Schering

LigandPNGBDBM84555(Indirubin derivative, 30a | Indirubin derivative, ...)
Affinity DataIC50: >1.00E+4nMpH: 7.0 T: 2°CAssay Description:Inhibition assay using CDK and selective kinases such as gsk3, EGFR, c-Kit, InsR and KDR.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Schering

LigandPNGBDBM84555(Indirubin derivative, 30a | Indirubin derivative, ...)
Affinity DataIC50: >1.00E+4nMpH: 7.0 T: 2°CAssay Description:Inhibition assay using CDK and selective kinases such as gsk3, EGFR, c-Kit, InsR and KDR.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKit ligand(Homo sapiens (Human))
Schering

LigandPNGBDBM84555(Indirubin derivative, 30a | Indirubin derivative, ...)
Affinity DataIC50: >1.00E+4nMpH: 7.0 T: 2°CAssay Description:Inhibition assay using CDK and selective kinases such as gsk3, EGFR, c-Kit, InsR and KDR.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKit ligand(Homo sapiens (Human))
Schering

LigandPNGBDBM84555(Indirubin derivative, 30a | Indirubin derivative, ...)
Affinity DataIC50: >1.00E+4nMpH: 7.0 T: 2°CAssay Description:Inhibition assay using CDK and selective kinases such as gsk3, EGFR, c-Kit, InsR and KDR.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Schering

LigandPNGBDBM84555(Indirubin derivative, 30a | Indirubin derivative, ...)
Affinity DataIC50: >1.00E+4nMpH: 7.0 T: 2°CAssay Description:Inhibition assay using CDK and selective kinases such as gsk3, EGFR, c-Kit, InsR and KDR.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Schering

LigandPNGBDBM84555(Indirubin derivative, 30a | Indirubin derivative, ...)
Affinity DataIC50: >1.00E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition assay using CDK and selective kinases such as gsk3, EGFR, c-Kit, InsR and KDR.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed