BDBM84745 CAS_136434-34-9::DULOXETINE::LY-248686::LY248686::USRE49340, Rank 5
SMILES CNCC[C@H](Oc1cccc2ccccc12)c1cccs1
InChI Key InChIKey=ZEUITGRIYCTCEM-KRWDZBQOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 163 hits for monomerid = 84745
Affinity DataKi: 0.790nMAssay Description:Ability to inhibit [3H]-paroxetine binding to cloned human serotonin (5-HT) transporterMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Ability to inhibit the reuptake of 5-HT at human serotonin transporterMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]nisoxetine from rat NET in rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Inhibition constant against serotonin transporterMore data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-dawley rat frontal cortex by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Inhibitory activity against Dihydrofolate reductase in Neisseria gonorrhoeaeMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]5HT from human 5HT transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.97nMAssay Description:Inhibition of human NETMore data for this Ligand-Target Pair
Affinity DataKi: 7.45nMAssay Description:Ability to inhibit [3H]-nisoxatine binding to cloned human norepinephrine (NE) transporterMore data for this Ligand-Target Pair
Affinity DataKi: 7.5nMAssay Description:Ability to inhibit the reuptake of NE at human norepinephrine transporterMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Inhibition constant against norepinephrine transporterMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 45nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 45nMAssay Description:Displacement of [3H]noradrenaline from human NET receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Ability to inhibit the reuptake of dopamine at human dopamine transporterMore data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Ability to inhibit [3H]-WIN-35,428 binding to cloned human dopamine (DA) transporterMore data for this Ligand-Target Pair
Affinity DataKi: 316nMAssay Description:Displacement of [3H]WIN35428 from human recombinant DAT transfected in HEK293 cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 370nMAssay Description:Inhibition constant against dopamine transporterMore data for this Ligand-Target Pair
Affinity DataKi: 435nMAssay Description:Displacement of [3H]dopamine from human DAT receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 435nMAssay Description:Displacement of [3H]dopamine from human DAT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rat)
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database