BDBM85330 CAS_68647::NSC_68647::ONDANSETRON::Ondansetron hydrochloride
SMILES: Cc1nccn1CC1CCc2c(C1=O)c1ccccc1n2C
InChI Key: InChIKey=FELGMEQIXOGIFQ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 0.770 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense Curated by ChEMBL | Assay Description Compound was evalated for its in vitro affinity at serotonergic 5-hydroxytryptamine 3 receptor by radioligand binding assay , using [3H]-LY 278584 in... | J Med Chem 42: 5020-8 (2000) Article DOI: 10.1021/jm991076c BindingDB Entry DOI: 10.7270/Q2H132PJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia & Upjohn Curated by ChEMBL | Assay Description In vitro affinity for 5-hydroxytryptamine 3 (5-HT3) receptor by displacement of [3H]BRL-43694 from rat entorhinal cortex | J Med Chem 40: 3369-80 (1997) Article DOI: 10.1021/jm970060o BindingDB Entry DOI: 10.7270/Q2X63NNK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Siena Curated by ChEMBL | Assay Description Binding affinity for 5-hydroxytryptamine 3 receptor from rat cortex using [3H]BRL-43694 as radioligand | J Med Chem 38: 2692-704 (1995) Article DOI: 10.1021/jm00014a021 BindingDB Entry DOI: 10.7270/Q27H1K7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Duphar B.V. Curated by ChEMBL | Assay Description Displacement of [3H]- GR-65,630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranes | J Med Chem 36: 3693-9 (1994) Article DOI: 10.1021/jm00075a026 BindingDB Entry DOI: 10.7270/Q2NS0SZH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Duphar B.V. Curated by ChEMBL | Assay Description The binding affinity of the compound was measured on imidazoline I2 receptor using [3H]- indazoxan as radioligand. | J Med Chem 36: 3693-9 (1994) Article DOI: 10.1021/jm00075a026 BindingDB Entry DOI: 10.7270/Q2NS0SZH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company Curated by ChEMBL | Assay Description Inhibitory activity against 5-hydroxytryptamine 1D receptor in rat cortical membranes using [3H]5-HT as a radioligand | J Med Chem 33: 3176-81 (1991) Article DOI: 10.1021/jm00174a013 BindingDB Entry DOI: 10.7270/Q2TM7BQG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company Curated by ChEMBL | Assay Description pKi value for inhibition of [3H]LY-278584 binding to 5-hydroxytryptamine 3 receptor | J Med Chem 33: 3176-81 (1991) Article DOI: 10.1021/jm00174a013 BindingDB Entry DOI: 10.7270/Q2TM7BQG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 3A (Homo sapiens (Human)) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | DrugBank Article PubMed | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S Curated by ChEMBL | Assay Description Displacement of [3H]granisetron from human 5HT3A receptor expressed in HEK293 cells by filter binding assay | J Med Chem 54: 3206-21 (2011) Article DOI: 10.1021/jm101459g BindingDB Entry DOI: 10.7270/Q2W37XFC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Syntex Research Curated by ChEMBL | Assay Description Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor in rat brain cortical membranes using radioligand [3H]quipazine | J Med Chem 36: 2645-57 (1993) Checked by Author Article DOI: 10.1021/jm00070a008 BindingDB Entry DOI: 10.7270/Q2GM88T8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Binding affinity to 5-hydroxytryptamine 3 receptor was determined in rat cerebro cortical membranes using [3H]quipazine. | Citation and Details BindingDB Entry DOI: 10.7270/Q2959KQ0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merrell Dow Research Institute Curated by ChEMBL | Assay Description Binding affinity to 5-hydroxytryptamine 3 receptor of neuronal in the afferent rabbit vagus | J Med Chem 33: 1594-600 (1990) Article DOI: 10.1021/jm00168a011 BindingDB Entry DOI: 10.7270/Q25Q4X94 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Louis Pasteur Curated by ChEMBL | Assay Description Compound was evaluated for its binding affinity for 5-hydroxytryptamine 3 receptor by measuring displacement [3H]GR-65630 in rat cerebral cortex | J Med Chem 41: 311-7 (1998) Article DOI: 10.1021/jm9705418 BindingDB Entry DOI: 10.7270/Q2N29XMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 3A (Homo sapiens (Human)) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | DrugBank Article PubMed | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AMRI Curated by ChEMBL | Assay Description Binding affinity to human HT3A receptor | Bioorg Med Chem Lett 20: 6538-41 (2010) Article DOI: 10.1016/j.bmcl.2010.09.038 BindingDB Entry DOI: 10.7270/Q2Z31ZVH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-HT3A Serotonin Receptor (Mus musculus (house mouse)) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 3.98 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by PDSP Ki Database | Synapse 35: 79-95 (2000) Article DOI: 10.1002/(SICI)1098-2396(200002)35:2 BindingDB Entry DOI: 10.7270/Q2XK8D4N | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin (5-HT) receptor (RAT) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Syntex Discovery Research Curated by PDSP Ki Database | J Pharmacol Exp Ther 267: 961-70 (1993) Article DOI: 10.1016/j.bioorg.2015.05.005 BindingDB Entry DOI: 10.7270/Q2125R5V | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 5.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merrell Dow Research Institute Curated by ChEMBL | Assay Description Potency at neuronal 5-hydroxytryptamine 3 receptors in the rabbit heart | J Med Chem 33: 1594-600 (1990) Article DOI: 10.1021/jm00168a011 BindingDB Entry DOI: 10.7270/Q25Q4X94 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 6.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Rh£ne-Poulenc Rorer Central Research Curated by ChEMBL | Assay Description The compound was evaluated for the binding affinity towards 5-hydroxytryptamine 3 receptor by displacement of radioligand [3H]GR-65630 | J Med Chem 35: 903-11 (1992) Article DOI: 10.1021/jm00083a015 BindingDB Entry DOI: 10.7270/Q20004BR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 6.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Rh£ne-Poulenc Rorer Central Research Curated by ChEMBL | Assay Description Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes. | J Med Chem 35: 895-903 (1992) Article DOI: 10.1021/jm00083a014 BindingDB Entry DOI: 10.7270/Q2SJ1M77 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 6.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra Curated by ChEMBL | Assay Description Displacement of binding of [3H]-BRL 43694 to 5-hydroxytryptamine 3 receptor in rat cerebral cortex | J Med Chem 36: 2745-50 (1993) Article DOI: 10.1021/jm00071a005 BindingDB Entry DOI: 10.7270/Q2FX7B2N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 7.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL | Assay Description Binding affinity against radioligand [3H]quipazine labeled 5-hydroxytryptamine 3 receptor sites in neuroblastoma-glioma (NG108-15) cells. | J Med Chem 36: 617-26 (1993) Article DOI: 10.1021/jm00057a011 BindingDB Entry DOI: 10.7270/Q25B034N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 7.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL | Assay Description Compound was evaluated for its ability to displace [3H]quipazine binding to 5-hydroxytryptamine 3 receptor sites in NG 108-15. | J Med Chem 35: 4893-902 (1992) Article DOI: 10.1021/jm00104a016 BindingDB Entry DOI: 10.7270/Q2BK1CZ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HTR3A (GUINEA PIG) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 9.62 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Syntex Discovery Research Curated by PDSP Ki Database | J Pharmacol Exp Ther 267: 961-70 (1993) Article DOI: 10.1016/j.bioorg.2015.05.005 BindingDB Entry DOI: 10.7270/Q2125R5V | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-HT3A Serotonin Receptor (Mus musculus (house mouse)) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc Curated by ChEMBL | Assay Description The binding affinity was measured for 5-hydroxytryptamine 3 receptor on NG 108-15 cell line of mouse neuroblastoma-glioma cells in presence of [3H]5 ... | J Med Chem 33: 3020-3 (1990) Article DOI: 10.1021/jm00173a017 BindingDB Entry DOI: 10.7270/Q2VM4FGR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-HT3A Serotonin Receptor (Mus musculus (house mouse)) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | PubMed | 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by PDSP Ki Database | NIDA Res Monogr 178: 440-66 (1998) BindingDB Entry DOI: 10.7270/Q23J3BH2 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 3A (Homo sapiens (Human)) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | DrugBank Article PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc Curated by ChEMBL | Assay Description In vitro binding affinity for the 5-hydroxytryptamine 3 receptor was determined with NG-108-15 mouse neuroblastoma-glioma cells | J Med Chem 33: 2721-5 (1990) Article DOI: 10.1021/jm00172a007 BindingDB Entry DOI: 10.7270/Q2CJ8F2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 3A (Homo sapiens (Human)) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | DrugBank Article PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc Curated by ChEMBL | Assay Description Binding affinity towards 5-hydroxytryptamine 3 receptor by displacement of [3H]2 in Neuroblastoma-Glioma NG-108-15 cells | J Med Chem 33: 2715-20 (1990) Article DOI: 10.1021/jm00172a006 BindingDB Entry DOI: 10.7270/Q2H995S5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc Curated by ChEMBL | Assay Description In vitro inhibition of rat liver dihydrofolate reductase. | J Med Chem 33: 13-6 (1990) Article DOI: 10.1021/jm00163a003 BindingDB Entry DOI: 10.7270/Q29S1RNB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CCKBR (RAT) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 680 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Duphar B.V. Curated by ChEMBL | Assay Description The binding affinity of the compound was measured on cholecystokinin type B receptor using [3H]- CCK-8 as radioligand. | J Med Chem 36: 3693-9 (1994) Article DOI: 10.1021/jm00075a026 BindingDB Entry DOI: 10.7270/Q2NS0SZH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (RAT) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 680 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Duphar B.V. Curated by ChEMBL | Assay Description The binding affinity of the compound was measured on sigma receptor using [3H]- (+)-3-PPP as radioligand. | J Med Chem 36: 3693-9 (1994) Article DOI: 10.1021/jm00075a026 BindingDB Entry DOI: 10.7270/Q2NS0SZH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin (5-HT) receptor (Rattus norvegicus (rat)) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Neurological Disorders and Stroke Curated by PDSP Ki Database | J Biol Chem 268: 18200-4 (1993) Article DOI: 10.1021/cb500917m BindingDB Entry DOI: 10.7270/Q2V1239R | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin (5-HT) receptor (Rattus norvegicus (rat)) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Neurological Disorders and Stroke Curated by PDSP Ki Database | J Biol Chem 268: 18200-4 (1993) Article DOI: 10.1021/cb500917m BindingDB Entry DOI: 10.7270/Q2V1239R | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HTR4 (RAT) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense Curated by ChEMBL | Assay Description In vitro affinity at serotonergic 5-hydroxytryptamine 4 receptor by radioligand binding assay using [3H]GR-113808 in rat striatum membranes. | J Med Chem 42: 5020-8 (2000) Article DOI: 10.1021/jm991076c BindingDB Entry DOI: 10.7270/Q2H132PJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 1 (5-HT1) receptor (RAT-Rattus norvegicus (rat)-Rattus norvegicus (Rat...) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB MMDB Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra Curated by ChEMBL | Assay Description Displacement of binding of [3H]5-HT to 5-hydroxytryptamine 1 receptor in rat cerebral cortex | J Med Chem 36: 2745-50 (1993) Article DOI: 10.1021/jm00071a005 BindingDB Entry DOI: 10.7270/Q2FX7B2N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HTR4 (RAT) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Duphar B.V. Curated by ChEMBL | Assay Description The binding affinity of the compound was measured on 5-hydroxytryptamine 4 receptor using [3H]- GR-113,808 as radioligand. | J Med Chem 36: 3693-9 (1994) Article DOI: 10.1021/jm00075a026 BindingDB Entry DOI: 10.7270/Q2NS0SZH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin/mu opioid receptor (Rattus norvegicus (rat)) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Duphar B.V. Curated by ChEMBL | Assay Description The binding affinity of the compound was measured on mu-opiate receptor using [3H]- naloxone as radioligand. | J Med Chem 36: 3693-9 (1994) Article DOI: 10.1021/jm00075a026 BindingDB Entry DOI: 10.7270/Q2NS0SZH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor protein alpha-7 subunit (Mus musculus) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description In vitro Binding affinity towards alpha-7 nAChR was determined | Bioorg Med Chem Lett 11: 319-21 (2001) Article DOI: 10.1016/s0960-894x(00)00670-3 BindingDB Entry DOI: 10.7270/Q2028S36 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Duphar B.V. Curated by ChEMBL | Assay Description The binding affinity was measured on muscarine M2 receptor using [3H]- N-Me-SCOPOL as radioligand. | J Med Chem 36: 3693-9 (1994) Article DOI: 10.1021/jm00075a026 BindingDB Entry DOI: 10.7270/Q2NS0SZH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 1B/1D receptor (Rattus norvegicus (Rat)) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Duphar B.V. Curated by ChEMBL | Assay Description The binding affinity of the compound was measured on 5-hydroxytryptamine 1B receptor using [3H]- serotonin as radioligand. | J Med Chem 36: 3693-9 (1994) Article DOI: 10.1021/jm00075a026 BindingDB Entry DOI: 10.7270/Q2NS0SZH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat)) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Duphar B.V. Curated by ChEMBL | Assay Description The binding affinity of the compound was measured on 5-hydroxytryptamine 1C receptor using [3H]- serotonin as radioligand. | J Med Chem 36: 3693-9 (1994) Article DOI: 10.1021/jm00075a026 BindingDB Entry DOI: 10.7270/Q2NS0SZH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HTR3A (GUINEA PIG) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 6.38E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Syntex Discovery Research Curated by PDSP Ki Database | J Pharmacol Exp Ther 267: 961-70 (1993) Article DOI: 10.1016/j.bioorg.2015.05.005 BindingDB Entry DOI: 10.7270/Q2125R5V | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by PDSP Ki Database | NIDA Res Monogr 178: 440-66 (1998) BindingDB Entry DOI: 10.7270/Q23J3BH2 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by PDSP Ki Database | NIDA Res Monogr 178: 440-66 (1998) BindingDB Entry DOI: 10.7270/Q23J3BH2 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by PDSP Ki Database | NIDA Res Monogr 178: 440-66 (1998) BindingDB Entry DOI: 10.7270/Q23J3BH2 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Imidazoline receptor 1 (I1R) (Homo sapiens (Human)) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Duphar B.V. Curated by ChEMBL | Assay Description The binding affinity of the compound was measured on imidazoline I2 receptor using [3H]- indazoxan as radioligand. | J Med Chem 36: 3693-9 (1994) Article DOI: 10.1021/jm00075a026 BindingDB Entry DOI: 10.7270/Q2NS0SZH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DOPAMINE (RAT) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Duphar B.V. Curated by ChEMBL | Assay Description The binding affinity of the compound was measured on dopamine receptor D1 using [3H]- dopamine as radioligand. | J Med Chem 36: 3693-9 (1994) Article DOI: 10.1021/jm00075a026 BindingDB Entry DOI: 10.7270/Q2NS0SZH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Duphar B.V. Curated by ChEMBL | Assay Description The binding affinity of the compound was measured on dopamine receptor D2 using [3H]- spiperone as radioligand. | J Med Chem 36: 3693-9 (1994) Article DOI: 10.1021/jm00075a026 BindingDB Entry DOI: 10.7270/Q2NS0SZH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H1 receptor (RAT) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Duphar B.V. Curated by ChEMBL | Assay Description The binding affinity of the compound was measured on histamine H1 receptor using [3H]- mepyramine as radioligand. | J Med Chem 36: 3693-9 (1994) Article DOI: 10.1021/jm00075a026 BindingDB Entry DOI: 10.7270/Q2NS0SZH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycine receptor alpha-4 chain (Mus musculus) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Duphar B.V. Curated by ChEMBL | Assay Description The binding affinity of the compound was measured on glycine receptor using [3H]- strychnine as radioligand. | J Med Chem 36: 3693-9 (1994) Article DOI: 10.1021/jm00075a026 BindingDB Entry DOI: 10.7270/Q2NS0SZH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Opioid receptors; mu & delta (Rattus norvegicus (rat)) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Duphar B.V. Curated by ChEMBL | Assay Description The binding affinity of the compound was measured on delta-opiate receptor using [3H]- dadle as radioligand. | J Med Chem 36: 3693-9 (1994) Article DOI: 10.1021/jm00075a026 BindingDB Entry DOI: 10.7270/Q2NS0SZH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-HT5B (RAT) | BDBM85330![]() (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) | KEGG UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Duphar B.V. Curated by ChEMBL | Assay Description The binding affinity of the compound was measured on tryptamine receptor using [3H]- tryptamine as radioligand. | J Med Chem 36: 3693-9 (1994) Article DOI: 10.1021/jm00075a026 BindingDB Entry DOI: 10.7270/Q2NS0SZH | |||||||||||
More data for this Ligand-Target Pair |
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