BDBM8535 4-[(1E)-{2-[1-(3-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]hydrazin-1-ylidene}methyl]pyridine::heterocyclic pyrimidyl hydrazone 1
SMILES COc1cccc(c1)-n1ncc2c(N=NCc3ccncc3)ncnc12
InChI Key InChIKey=SAPYVGYEUFHIAF-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 8535
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
The Rockefeller University
Curated by ChEMBL
The Rockefeller University
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
The Rockefeller University
Curated by ChEMBL
The Rockefeller University
Curated by ChEMBL
Affinity DataIC50: 6.30nMpH: 7.2 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-33P] ATP. Af...More data for this Ligand-Target Pair