BDBM85565 2-[4-(4-Chlorophenylsulfonyl)-Phenyl}-thiazole-4-yl-methyl-sulfamate, 3b

SMILES NS(=O)(=O)OCc1csc(n1)-c1ccc(cc1)S(=O)(=O)c1ccc(Cl)cc1

InChI Key InChIKey=LXOHIMDOJADTLR-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 85565   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
UniversitÀ

LigandPNGBDBM85565(2-[4-(4-Chlorophenylsulfonyl)-Phenyl}-thiazole-4-y...)
Affinity DataKi:  30nM ΔG°:  -10.3kcal/molepH: 7.4 T: 2°CAssay Description:Inhibition assay using human Carbonic anhydrase I and II and bovine carbonic anhydrase IV. More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
UniversitÀ

LigandPNGBDBM85565(2-[4-(4-Chlorophenylsulfonyl)-Phenyl}-thiazole-4-y...)
Affinity DataKi:  66nM ΔG°:  -9.79kcal/molepH: 7.4 T: 2°CAssay Description:Inhibition assay using human Carbonic anhydrase I and II and bovine carbonic anhydrase IV. More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
UniversitÀ

LigandPNGBDBM85565(2-[4-(4-Chlorophenylsulfonyl)-Phenyl}-thiazole-4-y...)
Affinity DataKi: >1.00E+3nM ΔG°: >-8.18kcal/molepH: 7.4 T: 2°CAssay Description:Inhibition assay using human Carbonic anhydrase I and II and bovine carbonic anhydrase IV. More data for this Ligand-Target Pair
In DepthDetails PubMed