BDBM8590 (3-Pyridylmethylene)indane 9a::3-{[(1E)-5-bromo-2,3-dihydro-1H-inden-1-ylidene]methyl}pyridine

SMILES Brc1ccc2\C(CCc2c1)=C\c1cccnc1

InChI Key InChIKey=QWAFSKBCSGIDRF-XYOKQWHBSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 8590   

TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8590((3-Pyridylmethylene)indane 9a | 3-{[(1E)-5-bromo-2...)
Affinity DataIC50:  1.94E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8590((3-Pyridylmethylene)indane 9a | 3-{[(1E)-5-bromo-2...)
Affinity DataIC50:  37nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Calcutta

Curated by ChEMBL
LigandPNGBDBM8590((3-Pyridylmethylene)indane 9a | 3-{[(1E)-5-bromo-2...)
Affinity DataIC50:  7.83E+3nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Calcutta

Curated by ChEMBL
LigandPNGBDBM8590((3-Pyridylmethylene)indane 9a | 3-{[(1E)-5-bromo-2...)
Affinity DataIC50:  7.83E+3nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Calcutta

Curated by ChEMBL
LigandPNGBDBM8590((3-Pyridylmethylene)indane 9a | 3-{[(1E)-5-bromo-2...)
Affinity DataIC50:  7.83E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed