BDBM86095 2-Cyanopyrrolidine Derivative, 24

SMILES CC(C)CC(NC(=O)C(=C\c1ccccc1)\c1ccccc1)C(=O)N1CCC[C@H]1C#N

InChI Key InChIKey=QJBXJTZHTYRHGA-ZUGJCSJQSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 86095   

TargetCathepsin B(Homo sapiens (Human))
The M. S. University Of Baroda

LigandPNGBDBM86095(2-Cyanopyrrolidine Derivative, 24)
Affinity DataKi:  5.30E+3nM ΔG°:  -7.14kcal/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
The M. S. University Of Baroda

LigandPNGBDBM86095(2-Cyanopyrrolidine Derivative, 24)
Affinity DataKi: >1.00E+5nM ΔG°: >-5.42kcal/molepH: 6.0 T: 2°CAssay Description:The fluorescence for the assay was monitored on a Varian Gemini spectrofluorometer with the excitation and emission wavelengths at 380 and 440nm. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed