BDBM86101 2-[Cyano(3-indolyl) methylene]-3-indolone, 1

SMILES O=C1C(Nc2ccccc12)=C(C#N)c1c[nH]c2ccccc12

InChI Key InChIKey=SGKBIGPQADGHEV-LGMDPLHJSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 86101   

TargetLinoleate 9S-lipoxygenase-4(Glycine max (Soybean) (Glycine hispida))
Pcsir Laboratories Complex

LigandPNGBDBM86101(2-[Cyano(3-indolyl) methylene]-3-indolone, 1)
Affinity DataIC50:  3.91E+4nMpH: 8.0 T: 2°CAssay Description:LOX inhibiting activity was measured by modifying the spectrophotometric method developed by Tappel. More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Pcsir Laboratories Complex

LigandPNGBDBM86101(2-[Cyano(3-indolyl) methylene]-3-indolone, 1)
Affinity DataIC50:  2.35E+4nMpH: 8.0 T: 2°CAssay Description:Butyrylcholinesterase activity-inhibiting activities were measured by a slightly modified spectrophotometric method developed by Ellman. DTNB was us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed