BDBM86234 CAS_64057-70-1::MDMA,S(+)::NSC_126235

SMILES CN[C@H](C)Cc1ccc2OCOc2c1

InChI Key InChIKey=SHXWCVYOXRDMCX-MRVPVSSYSA-N

Data  7 KI  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 86234   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM86234(CAS_64057-70-1 | MDMA,S(+) | NSC_126235)
Affinity DataKi:  74nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNorepinephrine transporter(RAT)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM86234(CAS_64057-70-1 | MDMA,S(+) | NSC_126235)
Affinity DataKi:  136nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM86234(CAS_64057-70-1 | MDMA,S(+) | NSC_126235)
Affinity DataKi:  142nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM86234(CAS_64057-70-1 | MDMA,S(+) | NSC_126235)
Affinity DataKi:  630nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in Sprague-Dawley rat brain cortical membrane after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM86234(CAS_64057-70-1 | MDMA,S(+) | NSC_126235)
Affinity DataKi:  3.31E+3nMAssay Description:Displacement of [3H]DOB from 5HT2A in Sprague-Dawley rat cortex membranes measured after 15 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM86234(CAS_64057-70-1 | MDMA,S(+) | NSC_126235)
Affinity DataKi:  6.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM86234(CAS_64057-70-1 | MDMA,S(+) | NSC_126235)
Affinity DataKi:  2.45E+4nMAssay Description:Displacement of [3H]-citalopram from SERT in Sprague-Dawley rat cortex, striatum and cerebellum-dissected brain after 60 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Macaca mulatta)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM86234(CAS_64057-70-1 | MDMA,S(+) | NSC_126235)
Affinity DataEC50:  7.40E+3nMAssay Description:Activation of rhesus monkey TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein assessed as cAMP accumulation by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM86234(CAS_64057-70-1 | MDMA,S(+) | NSC_126235)
Affinity DataEC50:  340nMAssay Description:Activity at SERT in rat synaptosomes assessed as release of [3H]HT after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM86234(CAS_64057-70-1 | MDMA,S(+) | NSC_126235)
Affinity DataEC50:  3.70E+3nMAssay Description:Activity at DAT in rat synaptosomes assessed as release of [3H]DA after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM86234(CAS_64057-70-1 | MDMA,S(+) | NSC_126235)
Affinity DataIC50:  1.35E+4nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in Sprague-Dawley rat brain cortical membrane after 3 hrs by liquid scintillation spectrometri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed