BDBM8640 (isoquinolinemethylene)indane 30b::5-{[(1Z)-5-fluoro-2,3-dihydro-1H-inden-1-ylidene]methyl}isoquinoline

SMILES Fc1ccc2\C(CCc2c1)=C/c1cccc2cnccc12

InChI Key InChIKey=RNIVQRPDPOQWHP-UVTDQMKNSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 8640   

TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8640((isoquinolinemethylene)indane 30b | 5-{[(1Z)-5-flu...)
Affinity DataIC50:  374nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8640((isoquinolinemethylene)indane 30b | 5-{[(1Z)-5-flu...)
Affinity DataIC50:  26nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Calcutta

Curated by ChEMBL
LigandPNGBDBM8640((isoquinolinemethylene)indane 30b | 5-{[(1Z)-5-flu...)
Affinity DataIC50:  1.94E+3nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Calcutta

Curated by ChEMBL
LigandPNGBDBM8640((isoquinolinemethylene)indane 30b | 5-{[(1Z)-5-flu...)
Affinity DataIC50:  1.94E+3nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Calcutta

Curated by ChEMBL
LigandPNGBDBM8640((isoquinolinemethylene)indane 30b | 5-{[(1Z)-5-flu...)
Affinity DataIC50:  1.94E+3nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed