BDBM8836 3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-(4-fluorophenyl)urea::N-[4-(4-Amino-6-methylthieno[2,3-d]pyrimidin-5-yl)-phenyl]-N -(4-fluorophenyl)urea::Thienopyrimidine deriv. 18

SMILES Cc1sc2ncnc(N)c2c1-c1ccc(NC(=O)Nc2ccc(F)cc2)cc1

InChI Key InChIKey=WGRSUBGGVRCDHQ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 8836   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8836(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50:  52nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8836(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50:  33nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8836(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50:  850nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8836(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50:  33.1nMAssay Description:Inhibition of cKITMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8836(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50:  851nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8836(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50:  52.5nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8836(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50:  33nMAssay Description:Inhibition of c-Kit by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed