BDBM8849 3-[4-amino-5-(4-{[(3-methylphenyl)carbamoyl]amino}phenyl)thieno[2,3-d]pyrimidin-6-yl]-N,N-dimethylpropanamide::3-{4-Amino-5-[4-(3-m-tolylureido)phenyl]thieno[2,3-d]-pyrimidin-6-yl}-N,N-dimethylpropionamide::Thienopyrimidine deriv. 53

SMILES CN(C)C(=O)CCc1sc2ncnc(N)c2c1-c1ccc(NC(=O)Nc2cccc(C)c2)cc1

InChI Key InChIKey=NNHRULFQQIVXMY-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 8849   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8849(3-[4-amino-5-(4-{[(3-methylphenyl)carbamoyl]amino}...)
Affinity DataIC50:  210nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8849(3-[4-amino-5-(4-{[(3-methylphenyl)carbamoyl]amino}...)
Affinity DataIC50:  930nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8849(3-[4-amino-5-(4-{[(3-methylphenyl)carbamoyl]amino}...)
Affinity DataIC50:  140nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8849(3-[4-amino-5-(4-{[(3-methylphenyl)carbamoyl]amino}...)
Affinity DataIC50:  209nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8849(3-[4-amino-5-(4-{[(3-methylphenyl)carbamoyl]amino}...)
Affinity DataIC50:  933nMAssay Description:Inhibition of cKITMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8849(3-[4-amino-5-(4-{[(3-methylphenyl)carbamoyl]amino}...)
Affinity DataIC50:  141nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8849(3-[4-amino-5-(4-{[(3-methylphenyl)carbamoyl]amino}...)
Affinity DataIC50:  930nMAssay Description:Inhibition of c-Kit by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed