BDBM8854 3-{4-[4-amino-6-(propan-2-yl)thieno[2,3-d]pyrimidin-5-yl]phenyl}-1-(3-methylphenyl)urea::N-[4-(4-Amino-6-isopropylthieno[2,3-d]pyrimidin-5-yl)phenyl]-N -(3-methylphenyl)urea::Thienopyrimidine deriv. 80

SMILES CC(C)c1sc2ncnc(N)c2c1-c1ccc(NC(=O)Nc2cccc(C)c2)cc1

InChI Key InChIKey=VNWDQYGXWXVPJM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 8854   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8854(3-{4-[4-amino-6-(propan-2-yl)thieno[2,3-d]pyrimidi...)
Affinity DataIC50:  130nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM8854(3-{4-[4-amino-6-(propan-2-yl)thieno[2,3-d]pyrimidi...)
Affinity DataIC50:  129nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Dalian University

Curated by ChEMBL
LigandPNGBDBM8854(3-{4-[4-amino-6-(propan-2-yl)thieno[2,3-d]pyrimidi...)
Affinity DataIC50:  575nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Dalian University

Curated by ChEMBL
LigandPNGBDBM8854(3-{4-[4-amino-6-(propan-2-yl)thieno[2,3-d]pyrimidi...)
Affinity DataIC50:  580nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed