BDBM9053 6-chloro-N-{6-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]hexyl}-1,2,3,4-tetrahydroacridin-9-amine::Hexylene-Linked Bis-(6-chloro)tacrine::Homodimeric Tacrine Analog 3g
SMILES Clc1ccc2c(NCCCCCCNc3c4CCCCc4nc4cc(Cl)ccc34)c3CCCCc3nc2c1
InChI Key InChIKey=IXRJZUFMXJZPOC-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 9053
Affinity DataIC50: 0.600nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Julius-Maximilians-University Of W£Rzburg
Curated by ChEMBL
Julius-Maximilians-University Of W£Rzburg
Curated by ChEMBL
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 10 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 312nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair