BDBM91610 10q::alpha7 agonists 10q

SMILES CC(=O)NCc1cn(nn1)[C@H]1C[C@@H]2CC[C@H](C1)[N+]2(C)C

InChI Key InChIKey=SZDYKWSYYPWQMN-ZSOGYDGISA-O

Data  6 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 91610   

TargetSoluble acetylcholine receptor(Aplysia Californica)
University Of California San Diego

LigandPNGBDBM91610(10q | alpha7 agonists 10q)
Affinity DataKi:  800nM ΔG°:  -8.17kcal/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSoluble acetylcholine receptor(Aplysia Californica)
University Of California San Diego

LigandPNGBDBM91610(10q | alpha7 agonists 10q)
Affinity DataKi:  900nM ΔG°:  -8.10kcal/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine-binding protein(Lymnaea stagnalis)
University Of California San Diego

LigandPNGBDBM91610(10q | alpha7 agonists 10q)
Affinity DataKi: >5.00E+3nM ΔG°: >-7.11kcal/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSoluble acetylcholine receptor(Aplysia Californica)
University Of California San Diego

LigandPNGBDBM91610(10q | alpha7 agonists 10q)
Affinity DataKi: >5.00E+3nM ΔG°: >-7.11kcal/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University Of California San Diego

LigandPNGBDBM91610(10q | alpha7 agonists 10q)
Affinity DataKi: >3.00E+4nM ΔG°: >-6.41kcal/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Mus musculus (house mouse))
University Of California San Diego

LigandPNGBDBM91610(10q | alpha7 agonists 10q)
Affinity DataKi: >3.00E+4nM ΔG°: >-6.41kcal/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of California San Diego

LigandPNGBDBM91610(10q | alpha7 agonists 10q)
Affinity DataEC50:  5.00E+3nMpH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed