BDBM92595 DAG-lactone (130C045)
SMILES CN(C)c1ccc(\C=C2\CC(CO)(COC(=O)c3ccc(cc3)N(=O)=O)OC2=O)cc1
InChI Key InChIKey=FYPSFKVUNBXRFF-BOPFTXTBSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 92595
Affinity DataKi: 1.54nM ΔG°: -11.7kcal/molepH: 7.4 T: 2°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
Affinity DataKi: 4.20E+3nM ΔG°: -7.16kcal/molepH: 7.4 T: 2°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase MRCK alpha(Homo sapiens (Human))
National Cancer Institute-Bethesda
National Cancer Institute-Bethesda
Affinity DataKi: 2.26E+4nM ΔG°: -6.18kcal/molepH: 7.4 T: 2°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase MRCK beta(Homo sapiens (Human))
National Cancer Institute-Bethesda
National Cancer Institute-Bethesda
Affinity DataKi: 2.26E+4nM ΔG°: -6.18kcal/molepH: 7.4 T: 2°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair