BDBM92595 DAG-lactone (130C045)

SMILES CN(C)c1ccc(\C=C2\CC(CO)(COC(=O)c3ccc(cc3)N(=O)=O)OC2=O)cc1

InChI Key InChIKey=FYPSFKVUNBXRFF-BOPFTXTBSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 92595   

TargetProtein kinase C delta type(Homo sapiens (Human))
National Cancer Institute-Bethesda

LigandPNGBDBM92595(DAG-lactone (130C045))
Affinity DataKi:  1.54nM ΔG°:  -11.7kcal/molepH: 7.4 T: 2°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

LigandPNGBDBM92595(DAG-lactone (130C045))
Affinity DataKi:  4.20E+3nM ΔG°:  -7.16kcal/molepH: 7.4 T: 2°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase MRCK alpha(Homo sapiens (Human))
National Cancer Institute-Bethesda

LigandPNGBDBM92595(DAG-lactone (130C045))
Affinity DataKi:  2.26E+4nM ΔG°:  -6.18kcal/molepH: 7.4 T: 2°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase MRCK beta(Homo sapiens (Human))
National Cancer Institute-Bethesda

LigandPNGBDBM92595(DAG-lactone (130C045))
Affinity DataKi:  2.26E+4nM ΔG°:  -6.18kcal/molepH: 7.4 T: 2°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed