BDBM92602 DHOD Inhibitor, 1::US8703811, 2

SMILES Cc1ccccc1C=Cc1cc(O)c2ccccc2n1

InChI Key InChIKey=NUTJRCJUMGYLIV-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 92602   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
Harvard Medical School

LigandPNGBDBM92602(DHOD Inhibitor, 1 | US8703811, 2)
Affinity DataIC50:  930nMAssay Description:Assay was determined using a continuous assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Harvard Medical School

LigandPNGBDBM92602(DHOD Inhibitor, 1 | US8703811, 2)
Affinity DataIC50:  560nMAssay Description:Assay was determined using a continuous assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium vivax)
Harvard Medical School

LigandPNGBDBM92602(DHOD Inhibitor, 1 | US8703811, 2)
Affinity DataIC50:  5.60E+3nMAssay Description:Assay was determined using a continuous assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM92602(DHOD Inhibitor, 1 | US8703811, 2)
Affinity DataIC50: >3.00E+4nMAssay Description:Assay was determined using a continuous assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM92602(DHOD Inhibitor, 1 | US8703811, 2)
Affinity DataIC50: >3.00E+4nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Harvard Medical School

LigandPNGBDBM92602(DHOD Inhibitor, 1 | US8703811, 2)
Affinity DataIC50:  560nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium vivax)
Harvard Medical School

LigandPNGBDBM92602(DHOD Inhibitor, 1 | US8703811, 2)
Affinity DataIC50:  5.60E+3nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (fumarate)(Saccharomyces cerevisiae)
Genzyme

US Patent
LigandPNGBDBM92602(DHOD Inhibitor, 1 | US8703811, 2)
Affinity DataIC50: >1.00E+4nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
Harvard Medical School

LigandPNGBDBM92602(DHOD Inhibitor, 1 | US8703811, 2)
Affinity DataIC50:  930nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In DepthDetails US Patent