BDBM92730 NSC332384, 2

SMILES COc1cccc(CN=Nc2cc(C)nc3cc4OCOc4cc23)c1

InChI Key InChIKey=PXKBFIHMHPIJQQ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 92730   

TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
University Of Pittsburgh

LigandPNGBDBM92730(NSC332384, 2)
Affinity DataKi:  220nMAssay Description:A fluorescenc-based molecular beacon assay to measure APE-1 protein activity and inhibition was performed as described.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
University Of Pittsburgh

LigandPNGBDBM92730(NSC332384, 2)
Affinity DataIC50:  1.01E+4nMAssay Description:In addition to the real-time fluorescence assay for studying inhibition of APE-1 activity, we also employed a gel-based assay to visualize and quanti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed