BDBM92788 WAG-005

SMILES CCCCc1oc2ccccc2c1C(=O)c1cc(I)c(OCCC[N+](C)(C)C)c(I)c1

InChI Key InChIKey=SOFIRHJYYHVQEA-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 92788   

TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University Of Wisconsin

LigandPNGBDBM92788(WAG-005)
Affinity DataIC50:  4.10E+4nMAssay Description:IC50 values of aminodarone analogues using JARID1A PHD3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University Of Wisconsin

LigandPNGBDBM92788(WAG-005)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of recombinant GST-tagged KDM5A PHD3 (1601 to 1660 residues) (unknown origin) using biotin-H3K4me3 ( 1 to 14 residues) peptide substrate b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM92788(WAG-005)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of recombinant GST-tagged KDM4A double tudor domain (895 to 1011 residues) (unknown origin) using biotin-H3K4me3 ( 1 to 14 residues) pepti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of growth protein 2(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM92788(WAG-005)
Affinity DataIC50:  1.05E+5nMAssay Description:Inhibition of recombinant GST-tagged ING2 PHD (201 to 281 residues) (unknown origin) using biotin-H3K4me3 ( 1 to 14 residues) peptide substrate by fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University Of Wisconsin

LigandPNGBDBM92788(WAG-005)
Affinity DataIC50:  8.20E+4nMAssay Description:Inhibition of KDM5A (M1 to L801 residues) PHD2/3 deletion mutant (unknown origin) demethylation activity preincubated for 10 mins followed by peptide...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University Of Wisconsin

LigandPNGBDBM92788(WAG-005)
Affinity DataIC50:  4.10E+4nMAssay Description:Displacement of H3K4me3 binding to Halo-tagged GST-fused KDM5A PHD3 domain (unknown origin) expressed in Escherichia coli by HaloTag-based peptide di...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University Of Wisconsin

LigandPNGBDBM92788(WAG-005)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of recombinant HQ5-Halo-tagged JARID1A PHD3 finger domain (unknown origin) expressed in BL21(DE3)pLysS cells after 1 hr by chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University Of Wisconsin

LigandPNGBDBM92788(WAG-005)
Affinity DataIC50:  5.62E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from recombinant His6-tagged human KDM5A (PHD3) (1542 to 1660 residues) ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 7A(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM92788(WAG-005)
Affinity DataIC50:  5.00E+4nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD-JmjC) (unknown origin) preincubated for 15 mins followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University Of Wisconsin

LigandPNGBDBM92788(WAG-005)
Affinity DataIC50:  8.20E+4nMAssay Description:Inhibition of KDM5A (M1 to L801 residues) PHD2/3 deletion mutant (unknown origin) demethylation activity preincubated for 10 mins followed by peptide...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 7A(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM92788(WAG-005)
Affinity DataIC50:  5.00E+4nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase PHF2(Homo sapiens)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM92788(WAG-005)
Affinity DataIC50:  7.40E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7C (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone lysine demethylase PHF8(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM92788(WAG-005)
Affinity DataIC50:  3.90E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7B (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed