BDBM92912 Aryl 1-indanylketone, 1

SMILES Oc1c(cc(cc1N(=O)=O)-c1cc(F)cc(c1O)N(=O)=O)C(=O)C1CCc2ccccc12

InChI Key InChIKey=BQHKHXCLONFLRD-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 92912   

TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92912(Aryl 1-indanylketone, 1)
Affinity DataKi:  520nM ΔG°:  -7.99kcal/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92912(Aryl 1-indanylketone, 1)
Affinity DataKi:  2.42E+3nM ΔG°:  -7.14kcal/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase-like 1(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92912(Aryl 1-indanylketone, 1)
Affinity DataKi:  2.90E+4nM ΔG°:  -5.77kcal/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase H(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92912(Aryl 1-indanylketone, 1)
Affinity DataKi: >1.00E+5nM ΔG°: >-5.09kcal/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase B(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92912(Aryl 1-indanylketone, 1)
Affinity DataKi: >1.00E+5nM ΔG°: >-5.09kcal/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase C(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92912(Aryl 1-indanylketone, 1)
Affinity DataKi: >1.00E+5nM ΔG°: >-5.09kcal/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed