BDBM92961 ThMP

SMILES Cc1c(CCOP(O)(O)=O)sc[n+]1Cc1cnc(C)nc1N

InChI Key InChIKey=HZSAJDVWZRBGIF-UHFFFAOYSA-O

Data  4 KI  1 Kd

PDB links: 10 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 92961   

TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
TBA

Curated by ChEMBL
LigandPNGBDBM92961(ThMP)
Affinity DataKi:  3.00E+6nMpH: 7.0Assay Description:Competitive inhibition of electric eel AChE using acetylthiocholine chloride as substrate at pH 7 by Michaelis-Menten plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
TBA

Curated by ChEMBL
LigandPNGBDBM92961(ThMP)
Affinity DataKi:  5.90E+6nMpH: 8.25Assay Description:Noncompetitive inhibition of electric eel AChE using acetylthiocholine chloride as substrate at pH 8.25 by Michaelis-Menten plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
TBA

Curated by ChEMBL
LigandPNGBDBM92961(ThMP)
Affinity DataKi:  9.30E+6nMpH: 7.0Assay Description:Noncompetitive inhibition of electric eel AChE using acetylthiocholine chloride as substrate at pH 7 by Michaelis-Menten plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
TBA

Curated by ChEMBL
LigandPNGBDBM92961(ThMP)
Affinity DataKi:  1.12E+7nMpH: 8.25Assay Description:Competitive inhibition of electric eel AChE using acetylthiocholine chloride as substrate at pH 8.25 by Michaelis-Menten plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThiamine-binding periplasmic protein(Escherichia coli (strain K12))
Cornell University

LigandPNGBDBM92961(ThMP)
Affinity DataKd:  2.30nMAssay Description:the kd for ThOH, ThMP and ThDP were determined using titration experiments in which the change in the intrinsic protein fluorescence was monitored as...More data for this Ligand-Target Pair