BDBM93172 Cathepsin Inhibitor, Column 2 Row 2

SMILES CC(NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(F)(F)F)C(=O)CNC(=O)Cc1cccc(c1)-c1ccccn1

InChI Key InChIKey=MFKDQBYQJMCGMB-JKDDQTOVSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 93172   

TargetCathepsin K(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM93172(Cathepsin Inhibitor, Column 2 Row 2)
Affinity DataKi:  90nMpH: 5.5Assay Description:Inhibitors were assayed against human liver Cathepsin L and B. Inhibitors were also evaluated for inhibition against purified recombinant Cathepsin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM93172(Cathepsin Inhibitor, Column 2 Row 2)
Affinity DataKi:  120nMpH: 5.5Assay Description:Inhibitors were assayed against human liver Cathepsin L and B. Inhibitors were also evaluated for inhibition against purified recombinant Cathepsin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM93172(Cathepsin Inhibitor, Column 2 Row 2)
Affinity DataKi: >1.00E+3nMpH: 5.5Assay Description:Inhibitors were assayed against human liver Cathepsin L and B. Inhibitors were also evaluated for inhibition against purified recombinant Cathepsin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed