BDBM9347 (2Z)-but-2-enedioic acid; 9-amino-1,2,3,4-tetrahydroacridin-1-ol::9-Amino-1 ,2,3,4-tetrahydroacridin-1-ol deriv. 1a::9-amino-1,2,3,4-tetrahydroacridin-1-ol maleate::CHEMBL23455::CHEMBL51934::HP-029

SMILES Nc1c2C(O)CCCc2nc2ccccc12

InChI Key InChIKey=HLVVITIHAZBPKB-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 9347   

TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9347((2Z)-but-2-enedioic acid; 9-amino-1,2,3,4-tetrahyd...)
Affinity DataIC50:  4.00E+3nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
TBA

Curated by ChEMBL
LigandPNGBDBM9347((2Z)-but-2-enedioic acid; 9-amino-1,2,3,4-tetrahyd...)
Affinity DataIC50:  53nMAssay Description:Inhibition of (BChE) Butyrylcholinesterase of horse serumMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAcetylcholinesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM9347((2Z)-but-2-enedioic acid; 9-amino-1,2,3,4-tetrahyd...)
Affinity DataIC50:  702nMAssay Description:Inhibition of Acetylcholinesterase in human red blood cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9347((2Z)-but-2-enedioic acid; 9-amino-1,2,3,4-tetrahyd...)
Affinity DataIC50:  4.80E+3nMAssay Description:In vitro inhibitory activity against acetylcholinesterase using rat striatal preparationsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM9347((2Z)-but-2-enedioic acid; 9-amino-1,2,3,4-tetrahyd...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Acetylcholinesterase in mouse red blood cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9347((2Z)-but-2-enedioic acid; 9-amino-1,2,3,4-tetrahyd...)
Affinity DataIC50:  3.64E+3nMAssay Description:Inhibition of acetylcholinesterase from rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9347((2Z)-but-2-enedioic acid; 9-amino-1,2,3,4-tetrahyd...)
Affinity DataIC50:  361nMAssay Description:Inhibition of Acetylcholinesterase in rat red blood cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM9347((2Z)-but-2-enedioic acid; 9-amino-1,2,3,4-tetrahyd...)
Affinity DataIC50:  164nMAssay Description:Inhibition of acetylcholinesterase (AChE) of human red blood cell (type XIII) by modified radiometric AChE assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
TBA

Curated by ChEMBL
LigandPNGBDBM9347((2Z)-but-2-enedioic acid; 9-amino-1,2,3,4-tetrahyd...)
Affinity DataIC50:  60nMAssay Description:Inhibition of acetylcholinesterase (AChE) in electric eel (type V-S) by modified radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9347((2Z)-but-2-enedioic acid; 9-amino-1,2,3,4-tetrahyd...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAcetylcholinesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM9347((2Z)-but-2-enedioic acid; 9-amino-1,2,3,4-tetrahyd...)
Affinity DataIC50:  954nMAssay Description:Inhibition of Acetylcholinesterase in monkey red blood cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed