BDBM9486 6-(1H-Imidazol-1-ylmethyl)-2H-chrome-2-thione::6-(1H-imidazol-1-ylmethyl)-2H-chromene-2-thione::Coumarin deriv. 35

SMILES S=c1ccc2cc(Cn3ccnc3)ccc2o1

InChI Key InChIKey=DUPWCRFJOVHQKN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 9486   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Bari

LigandPNGBDBM9486(6-(1H-Imidazol-1-ylmethyl)-2H-chrome-2-thione | 6-...)
Affinity DataAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Bari

LigandPNGBDBM9486(6-(1H-Imidazol-1-ylmethyl)-2H-chrome-2-thione | 6-...)
Affinity DataIC50:  1.13E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed